Establishment of a Tissue Sample Bank in the Field of Gynecologic Oncology
- Gender
- Women and men
- Age
- 18 years and older
- Trial type
- Observational
- Line of therapy
- all
- Phase
- —
What is this trial about?
To better understand and treat cancer, the systematic collection and analysis of tissue samples is of great importance to medical research. The goal of the Tumor Bank Study is to establish a comprehensive tissue bank containing samples from patients with various types of cancer as well as from healthy control subjects, in order to lay the foundation for future research in the field of cancer diagnosis and treatment. This is an observational study in which no new medications are being tested. Women and men between the ages of 18 and 90 with only one known benign or malignant tumor, as well as healthy control subjects, are eligible to participate in this study.
Trial flow
Requirements
Diagnosis: Malignant Neoplasms including Ovarian Neoplasms, Breast Neoplasms, Colorectal Neoplasms, Neoplasms of the Female Genitalia, Lung Neoplasms, Endocrine Gland Neoplasms; or benign neoplasm or inflammatory disease; or healthy controls
Age: 18–90 years
Key inclusion criteria: only one condition
Allocation
Stratifizierung anhand von Markern
Treatment
Follow-up
Diagnosis: Malignant Neoplasms including Ovarian Neoplasms, Breast Neoplasms, Colorectal Neoplasms, Neoplasms of the Female Genitalia, Lung Neoplasms, Endocrine Gland Neoplasms; or benign neoplasm or inflammatory disease; or healthy controls
Age: 18–90 years
Key inclusion criteria: only one condition
Stratifizierung anhand von Markern
Detailed description
Advances in cancer diagnosis and treatment are increasingly based on what is known as translational research, in which new scientific findings are translated into clinical practice as quickly as possible. A key prerequisite for this is the systematic collection of biological samples along with the associated clinical data. As part of this observational study, various biological samples are collected, including tumor tissue, abdominal fluid (ascites) and fluid in the pleural cavity (pleural effusion), urine, saliva, sputum, as well as stool samples and lavage fluids from diagnostic or therapeutic procedures. Tumor tissue is collected during planned surgical procedures, with pathological evaluation ensured first and only excess material used for research. Participation in the study does not alter patients’ regular treatment.
The goal of this observational study is to establish a comprehensive tissue bank containing samples from patients with various types of cancer as well as from healthy control subjects, in order to lay the foundation for future research in the field of cancer diagnosis and therapy. The collected samples will be used for a variety of investigations, such as the analysis of tumor markers—that is, characteristics that may provide clues about the course of the disease or the response to therapy. In addition, genetic changes in the cancer cells can be investigated, and disseminated tumor cells can be detected. The study covers various types of cancer, including ovarian cancer, breast cancer, colorectal cancer, lung cancer, tumors of the female reproductive organs, and tumors of the hormone-producing glands. Together with a complementary blood sample bank, this tissue bank forms a comprehensive foundation for oncological research.
Patients between the ages of 18 and 90 with a malignant tumor, patients with a benign or inflammatory disease serving as a control group, and healthy control subjects are eligible to participate. Patients must not have multiple tumors or a concurrent inflammatory and malignant condition.
Facts
- Which conditions: various types of cancer, including ovarian cancer, breast cancer, colorectal cancer, lung cancer, tumors of the female reproductive organs, and endocrine tumors, as well as individuals with benign conditions and healthy individuals
- Cancer characteristics: /
- What the study investigates: Establishment of a systematic tissue bank containing biological samples and clinical data for oncological research
- Study objective: Establishment of a tumor tissue bank as a foundation for future translational research to improve cancer diagnosis and treatment
- Study duration: 14-year observation period (September 2003 through December 2026, as projected)
- Study characteristics: Observational study, case-control design, three study groups
Trial sites
1 trial site in Germany is listed.
Charité – Universitätsmedizin Berlin
Augustenburger Platz 1, 13353 Berlin
Active, not recruiting
This list is compiled to the best of our knowledge but without guarantee: it may be incomplete, and a site's recruitment status can change at any time.
- Dr. med. Sebastian SommerSpecialist in internal medicine with a focus on hematology and oncology
- PD Dr. med. Matthias FröhlichSpecialist in internal medicine, immunology and emergency medicine
This description is based on the public trial registry (NCT01789229) and was translated into plain language by our medical editorial team. Whether participation is an option for you is a decision you make together with your treating physician.